It is all about diet and lifestyle! I.e.sugar and carbohydrates, stress and environmental toxins.
Anytime you consume sugar, or a carbohydrate of any kind, your blood sugar (glucose) levels increase. When blood sugar rises, then the pancreas is prompted to deliver insulin which directs your glucose receptors to open up and one of three things occur. The sugar is used immediately for energy, it gets stored as glycogen in the liver or muscle to be used as energy at a later day, or it is stored in the cell as fat as a long-term future energy source. At this point, your blood sugar will return to normal and insulin is no loner released.
If you eat sugar or carbohydrates frequently, then this process is going on all the time. Since the body can only burn so much sugar at one time, and the liver can only hold so much glycogen, then a great deal of it is getting stored as fat.
After a while, the glucose receptors recognize that there is too much fat in storage so they tell insulin they will not store anymore by refusing to open up, also known as insulin resistance. The pancreas says, “but this person keeps on pumping us with sugar and we can’t have all this sugar in the blood stream, so you have to open up,” and then it releases even more insulin. The glucose receptors get even more stubborn and push back harder, refusing to open up; and so the pancreas throws greater amounts of insulin at them in a desperate attempt to restore balance to blood sugar levels. At this point, insulin levels in the bloodstream are very high, which is called hyperinsulinism.
High levels of insulin increase the conversion of gamma linolinec acid into arachidonic acid, which results in higher than normal levels of arachidonic acid, which is converted into high levels of pro-inflammatory mediators known as prostaglandins and cytokines that results in inflammation, which puts one at risk of the long list of conditions and symptoms associated with inflammation. Inflammation = disease!!
Guess what kind of fat sugar is converted into? Triglycerides. And, when the glucose receptors prevent the fat from getting stored in the cell, then it is shuffled into very low density lipoprotein particles (also known as LDL on cholesterol tests) and gets recirculated into the blood stream. However, LDL occurs as two different types, one is large buoyant particles and the other is small very low-density lipoprotein particles known as VLDL. LDL is actually needed in the body to heal damaged vessels; it is the VLDL that is associated with clogged arteries and heart disease.
If you continue to put your body through this ferocious pattern by eating sugar or carbohydrates, then eventually the glucose receptors will completely stop acting in response to insulin and there will be both high levels of sugar and insulin in the bloodstream. The pancreas will then get wore out from its futile battle and will no longer be capable of generating insulin and moderating your blood sugar levels, which is known as type 2 diabetes.
This explains why obesity often occurs, and is associated with, many other health conditions like type 2 diabetes, inflammation, heart disease, high blood pressure, high triglycerides and high cholesterol.
Additionally, insulin increases another hormone called ghrelin which activates hunger, and decreases leptin, your hormone that tells that you are full. Therefore, you will never feel full and you will overeat.
Carbohydrates = Sugar = Insulin = fat The Imsyser team will share more on stress related weight issues in the next blog article. Call 086 010 3859 for more on any of our amazing health products designed to support weight management.