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Insulin Resistance Drives Chronic Disease

Insulin Resistance Drives Chronic Disease

Excessive amounts of refined sugar and processed fructose and grains cause insulin resistance, and most of the disease-promoting effects of a processed food diet can be traced back to this.

Insulin is a major accelerator of the ageing process, and also affects many bodily processes, all of which can impact your longevity. For example, insulin alters the expression of numerous hormones; stimulates your sympathetic nervous system; and promotes vasoconstriction.

As noted by Dr. Robert Lustig, many of the chronic diseases we struggle with today are in fact insulin resistance states. In essence, whichever organ becomes insulin resistant ends up manifesting its own metabolic syndrome.

For example, when you have insulin resistance of the liver, you end up with type 2 diabetes. When you have insulin resistance of the brain, you end up with Alzheimer’s disease. Insulin resistance of the kidney leads to chronic renal disease, and so forth.

To reduce your risk of disease, you want to keep your insulin levels as low as possible, and one of the quickest and easiest ways to do this is to avoid processed foods and sweetened beverages of all kinds.

As a standard recommendation, keep your total fructose consumption below 25 grams per day. If you are insulin resistant (and at least half of the American population is, whether overweight or not), you’d be wise to limit your fructose to 15 grams per day or less.

This may be particularly important if you have elevated uric acid levels, which can be used as a predictor for fructose toxicity. (For more information on this, please my previous interview with Dr. Richard Johnson.)

To counter the food industry’s propaganda that downplays the impact of a high-sugar, processed food diet, dozens of scientists at three American universities have created a new educational website called

The site is aimed at making independent research available to the public. To learn more about what the science really says about sugar, I highly recommend browsing through the site.

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